Fact Sheet: President Donald J. Trump Ensures American Pharmaceutical Supply Chain Resilience by Filling the Strategic Active Pharmaceutical Ingredients Reserve

President Trump Ensures American Pharmaceutical Supply Chain Resilience by Filling the Strategic Active Pharmaceutical Ingredients Reserve

Impact Score: 2.4

Timeline: N/A – No explicit deadline specified for achieving the six-month API supply or completing other actions.

Summary: This Executive Order aims to bolster U.S. pharmaceutical security by establishing a Strategic Active Pharmaceutical Ingredients Reserve (SAPIR) to ensure a reliable domestic supply chain for essential medicines. The Office of the Assistant Secretary for Preparedness and Response (ASPR) will identify critical drugs, stockpile a 6-month supply of domestic APIs, update the list of essential medicines, and plan a second SAPIR repository. This effort addresses vulnerabilities caused by limited domestic API production and emphasizes restoring American self-reliance through domestic manufacturing and competitive pricing. Vanderbilt University’s medical, engineering, and research programs may experience shifts in focus, funding, and collaboration opportunities relating to pharmaceutical supply chain resilience.

Key Actions: Vanderbilt University Medical Center should seek partnerships with pharmaceutical companies; the School of Medicine should develop educational programs on pharmaceutical manufacturing and supply chain management; the Office of Federal Relations must advocate for aligned research funding; and the Center for Health Policy should research policy implications of domestic production.